Sisophon experiences a hot and dry climate year-round. The coolest months are November to January, with temperatures ranging from 22-28°C, while the hottest period occurs from February to April, with temperatures frequently reaching above 30°C. March is particularly warm, with temperatures averaging 30°C. The region's temperature remains relatively consistent throughout the year, with minimal seasonal variation. The dry season typically lasts from November to May, with the wettest months being June to October.